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Adrenaline (Epinephrine) Devices - Fast Facts

This document has been developed by ASCIA, the peak professional body of clinical immunology/allergy specialists in Australia and New Zealand. ASCIA information is based on published literature and expert review, is not influenced by commercial organisations and is not intended to replace medical advice.

For patient or carer support contact Allergy & Anaphylaxis Australia or Allergy New Zealand.

pdfASCIA PC FAST FACTS Adrenaline Devices 2025128.32 KB

1. Adrenaline can save lives when used to treat anaphylaxis

ASCIA recommends adrenaline as the first line, emergency treatment for anaphylaxis (severe allergic reactions), using either of the two adrenaline device brands listed below, which are:

  • PBS listed in Australia since 2003 (EpiPen® is Pharmac listed in New Zealand since 2023).

  • Widely used in other countries.

Anapen® - Supplied by Arrotex             

EpiPen® -Supplied by Viatris
 Anapen device  EpiPen devices

Dose recommended by ASCIA

  • Anapen® 500*: Adults or children >50kg (>12 years)

Doses recommended by ASCIA:

  • EpiPen® Junior: Children 7.5-20 kg (~1-5 years)
  • EpiPen®: Adults or children >20kg (>5 years)
  • EpiPen®: Adults or children >50kg (>12 years) 

Abbreviations: (>) means greater than and (~) means approximately

*The dose of adrenaline in Anapen® 500 is consistent with the intramuscular injection (IMI) adrenaline dose recommendations in several publications for people who weigh more than 50kg.

2. It is important to know how to use Anapen® and EpiPen® devices

QR Code devicesAnapen® (4 steps) and EpiPen® (3 steps) are both injected into the outer mid-thigh, but have different instructions, which are on the device labels and the ASCIA website.

A general version of the ASCIA Action Plan for Anaphylaxis is available that include instructions for both devices.

Device specific plans include this QR code that links to instructions for both brands.

Instructions for both devices are included in ASCIA Anaphylaxis e-training courses.

3. Why is it important to have multiple brands of adrenaline devices?
  • To ensure continued supply of life saving adrenaline, particularly if one brand has stock shortages.
  • To encourage suppliers to provide devices with longer shelf life.
  • To provide a choice of dose, if prescribers prefer a higher dose (500 microgram device) for people >50kg, which may reduce the need for further adrenaline doses in older teens and adults >50kg.
  • To provide choice for consumers to access devices with points of difference to best suit their needs.

© ASCIA 2025

Content updated February 2025

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