Dietary Guide - Four Food Elimination Diet (4FED) for EoE
This document has been developed by ASCIA, the peak professional body of clinical immunology/allergy specialists in Australia and New Zealand. ASCIA information is based on published literature and expert review, is not influenced by commercial organisations and is not intended to replace medical advice. For patient or carer support contact Allergy & Anaphylaxis Australia, AuSEE or Allergy New Zealand.
Eosinophilic oesophagitis (EoE) happens when white blood cells (called eosinophils) build up in the lining of the oesophagus, which is the tube that connects the mouth to the stomach. This can be the result of an allergic reaction to food or the environment. Most cases of EoE are seen in people with other allergies such as allergic rhinitis (hay fever) and asthma. It is estimated to affect around one in 1,000 people (children and adults), and the frequency of EoE appears to be increasing. The reasons are unclear, but it is known that allergies of all types have become more common.
More information about EoE can be found on the ASCIA website:
www.allergy.org.au/patients/food-other-adverse-reactions/eosinophilic-oesophagitis
ASCIA PCC Dietary Guide EoE 4FED 2023217.28 KB
The 4FED diet eliminates 4 common trigger foods for EoE - cow’s milk (dairy), soy, egg and wheat
Diet Instructions
- This diet plan outlines how to follow a diet free from cow’s milk (dairy), soy, egg and wheat. The diet involves strictly avoiding all foods and drinks that contain cow’s milk (dairy), soy, egg and wheat even in very small quantities.
- This diet is to be used for 8 to 12 weeks as a trial to see if avoiding certain foods will help reduce symptoms. You should regard this diet as a test to see if foods are making symptoms worse and not necessarily a long term treatment.
- You will be asked to complete diaries recording foods eaten and details of any symptoms whilst following this diet.
- The effect of the diet will be assessed by symptoms and/or a repeat endoscopy (a procedure to look inside the body with a small tube with a camera and light attached), and biopsies (samples of cells) of the oesphagus are taken.
- Each food will then be reintroduced one by one. Introduction of foods will be discussed in detail by the doctor and dietitian at follow up appointments.
What foods can be eaten?
If you have existing food allergies it is important to continue to avoid those foods whilst following this diet for EoE. Otherwise, all plain meat, fish, chicken, legumes, non-wheat grains, fruits, nuts, seeds and vegetables can be included. Your specialist may recommend excluding all gluten containing grains (wheat, barley, rye and oats).
What about packaged foods?
Many packaged food products will contain ingredients made from wheat, soy, egg or milk. In Australia and New Zealand, food manufacturers must declare the presence of any cow’s (and other animal) milk (dairy), soy, egg, wheat and other gluten containing grains however small the amount. It is important to check package labels, including ingredients lists carefully, and avoid products with any of the ingredients in the following tables.
What are “may contain traces of” statements?
These statements are voluntary and used by manufacturers to indicate that the product may be contaminated with food allergen ingredients through processing and packaging. Products that do not directly contain cow’s milk (dairy), soy, egg or wheat as an ingredient but have a “may contain ______” style statement are safe to include on this diet.
The table below lists foods and ingredients that contain cow’s milk, soy, egg or wheat protein and should be avoided.
A2 milk |
Ghee (milk) |
Sour cream (soy) |
Acidophilus milk (milk) |
Globulin (egg) |
Soy (flavproteins) |
Albumin (egg) |
Gluten (wheat) |
Soya beans (soy) |
Apovitellin (egg) |
Ice-cream (milk) |
Soy bean paste (soy) |
Atta flour (wheat) |
Imitation egg product (egg) |
Soy bean sprouts (soy) |
Avidin (egg) |
Infant formula (cow, soy, goat milk based, partially hydrolysed) |
Soy desserts (soy) |
Bean curd (soy) |
Kamut (wheat) |
Soy flour (soy) |
Bulgar (wheat) |
Kefir (milk) |
Soy ice-cream (soy) |
Burghul (wheat) |
Malted milk (milk) |
Soy mayonnaise (soy) |
Butter (milk) |
Margarine (milk) |
Soy sauce (soy) |
Buttermilk (milk) |
Matzoh (wheat) |
Soy yoghurt (soy) |
Butter oil (milk) |
Milk (A2, full cream, fat free, low fat, skim, lactose free) |
Spelt (wheat) |
Butter fat (milk) |
Lactalbumin (milk) |
Tabouleh (wheat) |
Casein / caseinates (milk) |
Lactose free milk (milk) |
Tamari (soy) |
Cheese / cheese powder (including cow’s, goat, sheep and other animal milks) (milk) |
Lactoglobulin (milk) |
Tempeh (soy) |
Condensed milk (milk) |
Livetin (egg) |
Teriyaki (soy) |
Cottage cheese (milk) |
Low fat milk (milk) |
Tofu (soy) |
Cous cous (wheat) |
Lysozyme (egg) |
Textured/hydrolysed Vegetable Protein (TVP) (HVP) |
Cracker meal (wheat) |
Malted milk (milk) |
Triticale (wheat) |
Cream (milk) |
Milk derivative (milk) |
Wheat |
Cultured milk (milk) |
Milk powder (milk) |
Wheat bran, flour, germ, meal, starch (wheat) |
Curds (milk) |
Milk protein (milk) |
Wheat berries (Wheat) |
Custard (milk) |
Milk solids (regular, non-fat and skim milk) |
Whey (milk) |
Dairy solids (milk) |
Miso (soy) |
Yoghurt (milk) |
Dried milk/Dried milk solids (milk) |
Ovalbumin (egg) |
|
Dried egg (egg) |
Ovomucoid (egg) |
|
Durum (wheat) |
Ovovitelin (egg) |
|
Edamame (soy) |
Seitan (wheat) |
|
Evaporated milk |
Semolina (wheat) |
|
Farina (wheat) |
||
Fat free milk (milk) |
The table below lists ingredients that do not contain milk, egg, soy or wheat proteins and are safe to include whilst following this diet.
Wheat |
|
Soy |
Other legumes such as chickpeas or kidney beans and lentils are tolerated by most individuals allergic to soy. If you are unsure, speak to your clinical immunology/allergy specialist or dietitian. |
Milk |
Note: Lactose free products should not be consumed as part of the 4FED diet as they still contain normal amounts of cow’s milk protein. |
What foods can be included instead?
Cow’s milk substitutes
Cow’s milk can be an important source of energy, protein and calcium in the diet, especially for developing infants and children. Appropriate substitution is essential to ensure adequate growth and development (in children) and sufficient intake of calcium.
Rice, oat, nut, pea or coconut-based drinks are NOT suitable as a drink for children under 1 year of age due to inadequate amounts of energy, fat and protein. For children over 1 year of age these drinks should only be used after consultation with a clinical immunology/allergy specialist and/or dietitian with experience in paediatric food allergy to ensure your child is getting adequate nutrition.
Summary of cow’s milk and soy substitutes
Instead of: |
Use: |
Cow's milk or soy infant formula for a child less than 1 - 2 years of age |
Breast milk or appropriate formula as advised by your child’s medical specialist |
Cow's milk or soy drink for children over 1 - 2 years of age and adults |
Rice, oat, nut, coconut or pea based drinks - choose one with at least 120 mg calcium per 100 mL |
Yoghurt and custard |
Coconut or nut based yoghurts, custards and chia pudding – check labels carefully. Homemade desserts with milk substitute. |
Cheese |
Coconut or nut based cheese |
Ice cream |
Sorbet, milk and soy free icecream and gelato – check labels carefully |
Butter and margarine |
Oil or milk and soy free margarine |
Cream and mayonnaise |
Rice cream, dairy and soy free mayonnaise |
Chocolate |
Milk and soy free chocolate. Many chocolates contain soy lecithin which is tolerated by most people with soy allergy. Note that most dark chocolate (unless labelled ‘dairy free’) will contain milk, even if it is not included on the ingredient list, due to the difficulty of cleaning equipment when producing both milk and dark chocolate. |
A calcium supplement may need to be taken if inadequate volumes of milk replacement or specialised formula are taken. Your dietitian will assess this and discuss this with you if required.
Wheat substitutes
The biggest challenge when avoiding wheat as well as egg, soy and milk is finding alternative breads, cereals and pasta. Many wheat free/gluten free breads will contain egg, soy or milk as ingredients. Ask your dietitian about brands of bread or bread mixes that will be suitable.
The table below outlines some alternatives.
Instead of: |
Use: |
||
Breads, cereals, pastas made |
Breads, flours, cereals, pastas made from: |
||
Amaranth Arrowroot Barley Buckwheat Chickpea (besan) Coconut Corn (maize) Gluten-free flours |
Lentil Lupin Millet Oat Pea Polenta Potato Psyllium |
Quinoa Rice Rye Sago Soy Sorghum Tapioca |
|
Snacks such as muesli bars and muffins |
Rice and corn crackers/cakes, gluten free savoury biscuits and crackers, gluten free muesli and snack bars |
||
Treats such as biscuits and chocolate |
Plain salted potato chips, corn chips, rice chips, and gluten free sweet biscuits |
||
Beer (alcoholic and non-alcoholic) |
Brands made from hops or barley. Gluten free beer. |
Specialty food allergy products
There are many specialised food products that are wheat, soy, milk and egg free. These products can be found in the health food section of the supermarket, health food stores or specialised online allergy stores.
Online Specialty Allergy Stores Sunnybrook Health store Happy Tummies Hopper HQ Foodstore, Cafe and Online The Cruelty Free Shop Vegan Perfection |
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Many of your favourite recipes can be modified to be suitable for use whilst following this diet.
The table below outlines ingredients used in many recipes and the suitable substitute ingredient.
INGREDIENT
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ALLERGY ALTERNATIVE
|
Eggs It is possible to make cakes and muffins The texture of the product may be a little |
For baking (cakes and biscuits): 1 tsp egg replacer + 2 tbsp water 1 tsp baking soda + 1 tbsp water + 1 tbsp vinegar 1½ tbsp water + 1½ tbsp oil + 1 tsp baking powder 1½ tbsp ground flaxseed mixed with 3 tbsp warm water (let stand for a few minutes) 1 tbsp chia seeds, grind then mix with 3 tbsp water (let stand for a few minutes) Binding: ¼ cup mashed potato or pumpkin ½ cup mashed banana or pureed apple 1½ tbsp ground flaxseed mixed with 3 tbsp warm water (let stand for a few minutes) 1 tbsp chia seeds, grind then mix with 3 tbsp water (let stand for a few minutes) 1 tbsp chia seeds, grind then mix with 3 tbsp water (let stand a for few minutes) *Aquafaba is the viscous water in which legume seeds such as chickpeas have been cooked, which can be used as a replacement for egg whites. 3 tbsp liquid from canned chick peas with ½ tsp cream of tartar mixed with hand mixer to make meringue |
Cow’s Milk |
Other milk substitutes (rice, oat, nut, pea, coconut milk) |
Plain Wheat Flour |
Commercial gluten free plain flour |
Self-Raising Wheat Flour |
Commercial gluten free baking or self-raising flour |
Margarine |
Milk free margarine |
Wheat Based Baking Powder |
Wheat free baking powder |
Meal and snack ideas
Breakfast
Oat porridge (check label for wheat and or gluten traces) made with calcium added plant milk (such as rice, oat, almond, pea, coconut)
Gluten free cereal with calcium added milk substitutes
Gluten free packet mix or home-made pancakes with egg, wheat and milk substitute
Wheat free bread with toppings such as honey, jam, nut spreads
Cooked breakfast options such as wheat free baked beans, tomatoes, mushrooms, bacon, avocado with wheat free bread
Smoothie made with fruit, oats, seeds, calcium fortified alternative milk and yoghurt
Fruit or vegetable juice, calcium fortified alternative milk (in coffee or tea)
Lunch and dinner ideas
Plain grilled, BBQ or roast beef, chicken, lamb, fish with salad/vegetables and rice, quinoa, barley or millet based cous cous
Homemade crumbed chicken or fish using egg replacer and gluten free crumbs to coat
Risotto/fried rice dish
Barley, quinoa and other alternative grain based salads and other meals
Wheat free pasta with homemade tomato-based sauce or bolognaise sauce
Gluten free pizza base and toppings (use coconut cheese)
Meat or fish-based curry and vegetables with rice, rice noodles or Millet based cous cous
Rice cakes with hummus, avocado, nut spreads, sliced meats (check ingredients), salad vegetables
Gluten free wraps with chicken, lamb, beef or ham and salad
Rice paper rolls
Tacos or burritos with corn-based taco shells or gluten free wraps
Baked potato or sweet potato with various toppings
Baked beans, (or other cooked breakfast options) on wheat free toast
Snacks
Smoothies made with calcium fortified alternative milk or yoghurt
Ice blocks with calcium fortified alternative milk or yoghurt
Homemade cakes and biscuits
Protein or energy balls made with ingredients such as ground nuts, honey, cocoa, soy free plant based protein powder, dried fruit and coconut
Fresh and dried fruit
Calcium fortified alternative custard, ice-cream or yoghurt with fruit
Plain popcorn
Corn chips, rice crackers with tomato salsa, nut butters or avocado
Plain potato chips
Jelly
Salsa or hummus dip with rice crackers or vegetable sticks
Nuts and nut butters
Note: The food lists included in this document are not exhaustive. People with food allergy should check foods labels each time products are purchased.
© ASCIA 2023
Content updated 2021
Format updated June 2023
For more information go to www.allergy.org.au/patients/food-allergy and
www.allergy.org.au/patients/food-other-adverse-reactions
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